In the late nineteenth century, a German biochemist found the nucleic acids, long-chain polymers of nucleotides, were made up of sugar, phosphoric acid, and several nitrogen-containing bases.

In the first step, the nucleic acids (siRNA or pDNA) are electrostatically condensed by complexation with polycations (decaarginine- or 2.5 kDa polyethylenimine-modified β-cyclodextrin) to form ...

Aayush Aayush (Purdue University photo/Steve Scherer) “The data shows our agile nanocarrier is flexible in its targeting ability, cargo size and disassembly kinetics,” Aayush said. “It provides an ...