DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

Peptide nucleic acids ... compared with the repulsion caused by DNA’s negatively charged phosphate ... By simply adding a substituent like a hydroxymethyl group a few carbons down ...

In 1919, Russian biochemist, Phoebus Levene proposed that nucleic acids are made up of nucleotides, which are composed of one of the four bases – A (adenine), T (thymine), G (guanine) and C ...

OUR earlier work on the chemical action of X-rays on the nucleic acids in aqueous systems1 has led us to suggest that labile compounds, including labile phosphate esters, are formed on irradiation ...

Scientists visualize how a vital hepatitis C virus protein moves along its nucleic acid substrate ... A key component of this process is unidirectional movement of a phosphate group in the middle ...

The addition of a phosphate group ... inducing a conformational change or affecting its interactions with other proteins or nucleic acids. For example, in transcription, ...