Notch is the receptor in a highly conserved signalling pathway that is crucial in development and implicated in malignant transformation. The basic paradigm ... The diagrams (a) represent Notch ...

The notch signaling pathway plays a major role in regulating various cellular processes during development, therefore dysregulation of this pathway can lead to disease. This basic signaling ...

despite the fact that the core pathway is very simple. Many different types of regulation contribute to the differing outcomes of Notch signalling, ranging from tissue-level coordination to ...

WEST LAFAYETTE, Ind. - A Purdue University study shows that Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity ...