Most of the human genome — 98 percent — is made up of DNA but doesn’t actually encode genes ... observed the resulting changes in gene expression. “One example that stood out was a non-coding mutation ...

Nearly 200 mutations in non-coding DNA have been identified to play a functional ... the resulting changes in gene expression. "One example that stood out was a non-coding mutation affecting ...

For example, sometimes our cells make RNA molecules ... some of which came to be used in confusing–and sometimes careless–ways. “Non-coding DNA” came to be a shorthand for DNA that didn ...

Non-coding DNA variants contribute to acute lymphoblastic ... they can figure out how it affects cancer's response to treatment. For example, the top variant from the screen led to the discovery ...

It turns out that the remainder of human DNA in the genome, the non-coding regions ... and enhancing the protein-coding genes -- turning them "on" and "off," for example. In this study, the ...

Begun's laboratory discovered a few years ago that new genes could also appear from previously non-coding stretches of DNA, and similar effects have since been discovered in other animals and plants. ...

Life on Earth reached a decisive turning point about 2.6 billion years ago. An international team of researchers has just ...

For example, the top variant from the screen ... The study serves as a proof of principle of how to take non-coding DNA variants and mechanistically connect them to a trait, such as chemotherapy ...