Scientists from the Burnham Institute for Medical Research and the University of Vermont have captured the first 3-dimensional (3D) atomic-resolution images of the motor protein myosin V as it ...

Conformational changes within myosin lead to its movement relative to an actin filament. Several crystal structures exist for myosin bound to various nucleotides, but none with bound actin ...

With intensifying global warming and climate change, drought has become a major threat to global agriculture, impacting crop ...

While their functions are diverse, myosins are similar in structure. NMII is so much like cardiac myosin, which keeps the ...

This study explores the use of polarized second-harmonic generation (pSHG) to investigate myosin conformation in the relaxed state, differentiating between the actin-available, disordered (ON) state ...

The experimental image shows two proteins -- myosin (cyan) and actin (red) -- in a chick embryo during gastrulation, highlighting the main body axes and the dominant force-generating regions (cyan).

Students will utilize in vitro and in vivo transcription assays to analyze the function and regulation of nuclear actin and nuclear myosins.

Myosin modulators were identified by testing these selected compounds using biochemical assay. The biochemical assays were made using bovine cardiac myosin S1 and rabbit skeletal F-actin.

Myosin V has two "legs" connected to a "body," but exactly how the protein molecule moves its load along helical fibers of actin has been a mystery. "Studies have suggested two main models for ...

In the process, they made an unexpected discovery: myosin, one of the three main proteins that make up striated muscle fibers, appears to enter the Z-disc. Models of how myosin, actin and the ...

As expected, PP1c was translocated to the cell membrane upon blue light illumination being exposed upon the OptoMYPT expressing cells, and consequently, actin and myosin-mediated contractile force ...