Key takeaways: 58% of patients had at least one mucus plug. Patients with four or more mucus plugs had a median FEV 1 of about 50%.; 82% of patients with a plug at baseline had a plug at year 3.

Adults with moderate to severe uncontrolled asthma experienced reductions in mucus plug scores with tezepelumab, according to a study published in NEJM Evidence.These reductions also correlated ...

Dupilumab (Dupixent), an interleukin (IL)-4/IL-13-blocking antibody, significantly reduced nitric oxide levels compared to placebo and reduced mucus plug scores by as early as 4 weeks, according ...

The researchers found that the absolute change from baseline in mean mucus plug score was −1.7 in patients receiving tezepelumab and 0.0 in patients receiving placebo.

Meeting Coverage > AAAAI Dupilumab Cuts Lung Inflammation, Breaks Up Mucus Plugs in Asthma Patients — In VESTIGE trial, IL-4/IL-13 blocker also improved airway volumes and airflow ...

Losing your mucus plug signals that labor may be approaching. Here’s what you need to know about why it happens, what to expect, and what to do next.