Motor neuron disease (MND) is a devastating condition that causes progressive muscle weakness by damaging the motor neurons, the nerve cells that connect the brain to muscles. These neurons allow ...

ALS also causes lower motor neuron symptoms like decreased muscle tone and twitches, where PLS only causes upper motor neuron symptoms.

Researchers have identified a protein that improves muscular metabolism, motor coordination and exercise performance in mice. The findings could be of therapeutic value for patients with muscle ...

Symptoms of motor neuron degeneration could start at as early as 3 months of age and lead to muscle atrophy, paralysis and death, often before the child's second birthday.

"Initiation of a Phase 2 clinical study of SB-509 in subjects with a motor neuron and muscle disease such as ALS is an obvious next step in the evaluation of this novel therapeutic," stated Dale ...