DNA methylation, a form of epigenetic modification, involves the addition of a methyl group to the cytosine bases of the DNA, altering its accessibility in chromatin and modulating gene expression.

Why normal cells turn into cancer cells One of the factors is deeply related to the failure of the cell differentiation mechanism called DNA methylation (*1). The joint research groups of The ...

This SRC is focused on the role of Methylation Dynamics in nuclear and cytoplasmic biological processes and how this modification impacts development, epigenetic cellular identity, tissue homeostasis ...

The research team decided to investigate the mechanism of faithful "DNA methylation inheritance" which is critical for cancer suppression and has not been sufficiently investigated.

DNA methylation is known to be catalyzed by DNA methyltransferases (DNMTs), but the mechanisms of demethylation are less clear. Some have proposed that demethylation takes advantage of mechanisms that ...

Overall, the team's findings thus suggest that DNA methylation is a crucial mechanism mediating the influence of early life experiences on mental health outcomes in early adolescence.

More information: Xianwei Song et al, Inheritance of acquired adaptive cold tolerance in rice through DNA methylation, Cell (2025). DOI: 10.1016/j.cell.2025.04.036 ...

H3K9 methylation is an epigenetic mark associated with turning off DNA transcription. Even though H3K9 methylation was discovered 25 years ago, not all of its molecular mechanisms have been clarified.

Epigenetic mechanism can explain how chemicals in plastic may cause lower IQ levels Date: May 20, 2021 Source: Uppsala University Summary: The chemical bisphenol F (found in plastics) can induce ...