Scientists have long known that psychedelics like LSD can help the brain grow new connections. These drugs promote something ...

Scientists at the University of California, Davis have developed a new drug related to LSD that retains the psychedelic’s ...

In a model where mice had been stressed to the point of losing ... “No one really wants to give a hallucinogenic molecule like LSD to a patient with schizophrenia. The development of JRT emphasizes ...

They used that structure to model the 5HT2a until Roth’s group worked out the crystal structure of 5HT2a. The compounds had been selected from a computational library of 75 million candidates.

Finally, new molecular sites and modes of LSD action continue to be uncovered 47. More research is needed to specify risperidone's molecular and cellular mechanisms.

Reference: Tuck JR, Dunlap LE, Khatib YA, et al. Molecular design of a therapeutic LSD analogue with reduced hallucinogenic potential. Proc Nat Acad Sci USA . 2025. doi: 10.1073/pnas.2416106122 This ...

Psychedelic drugs, such as lysergic acid diethylamide (LSD), can increase neuronal growth, which can have therapeutic effects for conditions such as schizophrenia. However, such drugs can induce ...

A model of the molecule LSD. Adobe. W hat’s a hallucinogen without the hallucinations? Perhaps a potent and fast-acting antidepressant, according to a new study based on virtual drug screening.

UC Davis researchers have developed a new, neuroplasticity-promoting drug closely related to LSD that harnesses the psychedelic’s therapeutic power with reduced hallucinogenic potential.

LSD and many of its other analogs have been made by extracting lysergic acid from ergot fungus and then chemically altering its structure. The molecule Olson wanted to make required a completely ...