They then showed that blocking the CTLA-4 pathway in those cells led to severe intestinal inflammation. To see if their results applied to humans, the investigators turned to the Jill Roberts ...

The data could help shed fresh light on how pathogen recognition proteins function and the role they play in certain chronic inflammatory ... humans and plants share a common pathogen recognition ...

Investigators have identified a new cellular pathway that may help explain how arterial inflammation develops ... along with human cells cultured in a petri dish, the team discovered that several ...

Postdoctoral researcher Yanan Ma, PhD, led a project that investigated a cancer-linked inflammation pathway in zebrafish ... While OXER1 is present in humans and in most larger mammals, like cats and ...

By harnessing natural inhibitory pathways like ... rejection and increased inflammation. The researchers also looked at the levels of the receptors in samples from human transplant biopsies ...

"In our study, we focused on a molecule called miRNA-27a, which we found to exert an anti-inflammatory effect by suppressing the NF-κB pathway but may also promote tissue regeneration by ...