In the current study researchers examined the specific mechanisms by which vitamin D might act on immune and inflammatory pathways. They incubated human white blood cells with varying levels of ...

They then showed that blocking the CTLA-4 pathway in those cells led to severe intestinal inflammation. To see if their results applied to humans, the investigators turned to the Jill Roberts ...

“Activation of these inflammatory pathways in the body and brain is one of the ways through which depressive symptoms can be produced,” said Charles Raison, a professor of human ...

The data could help shed fresh light on how pathogen recognition proteins function and the role they play in certain chronic inflammatory ... humans and plants share a common pathogen recognition ...

The research — published March 10, in the journal Cell Reports — shows that saturated fats “short-circuit” both mouse and human immune cells, producing an inappropriate inflammatory response as a ...

Investigators have identified a new cellular pathway that may help explain how arterial inflammation develops ... along with human cells cultured in a petri dish, the team discovered that several ...

Postdoctoral researcher Yanan Ma, PhD, led a project that investigated a cancer-linked inflammation pathway in zebrafish ... While OXER1 is present in humans and in most larger mammals, like cats and ...

"In our study, we focused on a molecule called miRNA-27a, which we found to exert an anti-inflammatory effect by suppressing the NF-κB pathway but may also promote tissue regeneration by ...