N6-methyladenosine (m6A) serves as a critical RNA modification, dynamically governing RNA metabolism through its influence on RNA stability, splicing, ...

Epigenetics, the mechanisms that control gene expression via modifications made to DNA, operate through two key approaches in eukaryotes. The first, histone modification, involves the modification of ...

The activity of these "switches" is regulated by their methylation status, chemical marks that can be added to or removed ...

BOSTON--(BUSINESS WIRE)--DeepCure, a therapeutics company using AI to discover novel drugs for inflammation and immune diseases, today announced the selection of its first development candidate ...

Discover how histone modifications unlock secrets of human aging, rivaling the precision of DNA methylation in decoding biological age. Study: Histone mark age of human tissues and cell types .

In males, a protein called KDM3A is responsible for removing this histone methylation, allowing the Sry gene to become active. We already knew that KDM3A requires iron for its enzymatic activity.