As well as being essential in the precise packaging of DNA into the space of the nucleus, histone proteins are also the site ...

The following is a summary of “Histone Modifications and DNA Methylation in Psoriasis: A Cellular Perspective,” published in the January 2025 issue of Allergy and Immunology by Pan et al. Epigenetic ...

New research has investigated the mechanism by which bivalency functions to poise genes for expression during cell differentiation, providing insight into a long-standing paradigm in the regulation of ...

The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed ...

The research could contribute to the development of more effective anti-aging treatments in the future. The body's aging ...

How? Scientists are using ChIP and PCR to find out. To examine changes in histone modification during blood cell development in chickens, the investigators started with whole chromatin from ...

Short-chain fatty acids (SCFAs) like propionate and butyrate are critical byproducts of dietary fiber digestion. These molecules do more than fuel the body—they directly influence gene expression and ...

Co. Ltd. has described histone acetyltransferase KAT6A (monocytic leukemia zinc finger protein; MOZ; MYST-3) and/or histone acetyltransferase KAT6B (MOZ2; MYST-4) inhibitors reported to be useful for ...

Newer treatments target pathways like Delta-like ligand 3, poly-ADP-ribose polymerase, and histone deacetylase to address ...

Epigenetic regulation relies on the dynamic modification of the two building blocks of chromatin: DNA and histone packaging proteins, to establish and maintain cell identity and fate. We develop and ...

Results prove that inversions can be generated in plants without causing further unwanted changes in the expression of genetic information.