Nature Medicine - Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. ... Figure 1: Liver histology of the FAH−/− mice 7 months after bone marrow transplantation.

Grouping based on histology and K19 expression in hepatocytes compared with the results of the grading, staging, and clinicopathological markers. Tables. Table 2.

Studies in laboratory animals and humans indicate that bone marrow stem cells can give rise to hepatic oval cells, hepatocytes, cholangiocytes, 2–4 skeletal-muscle cells, 5,6 astrocytes, and ...

The new method induced hepatocytes to expand for up to 40 population doublings, producing 1013 to 1016 cells from a single human hepatocyte isolate. By comparison, only 109 cells can typically be ...

Hepatocytes generated from iPSCs of different germ-layers secreted liver proteins into blood. Researchers have demonstrated that mature and immature liver cells generated from induced pluripotent ...