Thus, the glucocorticoid receptor is a double-edged sword in prostate cancer. Due to it promoting the development of drug resistance in prostate cancer, it was shown to have oncogenic effects.

SAN FRANCISCO -- Crinecerfont (Crenessity) may help improve metabolic profiles of adults and children with classic congenital ...

Thus, the glucocorticoid receptor is a double-edged sword in prostate cancer. Due to it promoting the development of drug resistance in prostate cancer, it was shown to have oncogenic effects.

Patients receiving ABBV-154 had a lower cumulative glucocorticoid dose by week 24 than those on placebo (mean difference, −164.8 mg for 150 mg; P = .007 and −182.6 mg for 340 mg; P = .003).

This study showed that the glucocorticoid receptor can only use regulatory regions that are already active in prostate cancer cells." Laura Helminen, Doctoral Researcher, University of Eastern Finland ...

Epidural glucocorticoid injection is primarily recommended for radicular pain, which is pain that extends into the leg, as opposed to nonradiating axial pain. The diagnosis of the underlying ...

In the PULSE-MI trial, prehospital pulse-dose glucocorticoid treatment in STEMI patients did not reduce the final infarct size at 3 months, despite improvements in acute outcomes.

Glucocorticoids have been the mainstay of treatment in patients with this condition. 3,6–8 Although moderate doses of glucocorticoids (15 to 20 mg of prednisone) can control disease, more than ...

Stefanie J. Siller, Dustin R. Rubenstein, A Tissue Comparison of DNA Methylation of the Glucocorticoid Receptor Gene (Nr3c1) in European Starlings, Integrative and Comparative Biology, Vol. 59, No. 2 ...