One devastating genetic disorder that exemplifies these difficult ethical and social concerns is Huntington's disease (HD). Symptoms of HD, which include uncontrolled movements, loss of mental ...

Huntington’s disease (HD) is a genetic brain disease. HD causes the gradual breakdown of nerve cells in the brain. Huntington’s disease is a progressive disorder that gets worse over time. Most people ...

Genetic tests: These test for CAG repetitions and are the gold standard test. If a doctor thinks a person may have HD, they will refer them to a neurologist. Treatment for Huntington’s disease ...

These kinds of studies are starting to touch on something more intimate than simply the search for new medicines, instead revealing new connections between our genetic code and our life choices.

Thus, choosing to have genetic testing for HD is highly personal, and it is recommended that individuals considering HD testing have extensive pretest counseling.

Purpose: Diagnostic and predictive testing for Huntington disease requires an accurate measurement of CAG repeats in the HD (IT15) gene. However, precise repeat sizing can be technically ...

The United States Bankruptcy Court for the District of Delaware approved this week the sale of the business assets of Benson Hill, St. Louis, to Confluence Genetics, LLC. This sale, which closed ...

Genetic Variant in FGF23 Tied With Cardiovascular Risks in HD. ... (HD) who suffer from secondary hyperparathyroidism (SHPT): rs11063112, a single-nucleotide polymorphism ...

HD is a genetic disease which also occurs in several other species. Dogs are not born with HD, but genetically disposed puppies can develop varying degrees of HD.

Using RNAi to reduce the levels of individual cellular proteins, the team carried out a genome-wide screen in a human cell model of HD of more than 7,800 genes viewed as potential drug targets.

More information: Zheng Ning et al. High-definition likelihood inference of genetic correlations across human complex traits, Nature Genetics (2020).DOI: 10.1038/s41588-020-0653-y ...