Etravirine, the latest approved NNRTI, shows potent antiretroviral activity against most nevirapine- and efavirenz-resistant HIV-1 strains, and demonstrates a high genetic barrier to resistance ...

Dolutegravir is an HIV integrase strand transfer inhibitor ... Dolutegravir is considered to have a high genetic barrier to resistance and requires selection of the Q148 + ≥2 additional ...

HIV drugs are also characterised by a barrier to resistance. This term is used to explain how quickly the virus can become resistant to a given drug if doses are missed. Fortunately, many of the newer ...

Doravirine and islatravir have complementary resistance profiles which results in a high genetic barrier to resistance ... ISL dose as a potential new daily HIV treatment option.

Our goal is to understand how virus evolution is influenced by genetic variation ... viruses – HIV and SIV). Among other things, we are interested in the interactions between these viruses and host ...

Kenyans with HIV will access a single-pill HIV treatment ... fewer drug interactions, and higher genetic barrier to resistance. It is with this in mind that, in July this year, Kenya approved ...

"An effective antiretroviral regimen can be devised for most people living with the virus; however, some people living with HIV no longer have durable viral suppression, due to resistance to ...