New research reveals significant differences in gene expression related to metabolism, inflammation and cardioprotection in the fat tissue of lean and obese mice. These findings could advance the ...

More information: Jiacheng Gu et al, Mapping multimodal phenotypes to perturbations in cells and tissue with CRISPRmap, Nature Biotechnology (2024). DOI: 10.1038/s41587-024-02386-x ...

A new study has shown that virus-like transposons, called Mavericks, are responsible for horizontal gene transfer (HGT) in nematodes. Researchers led by Alejandro Burga at the Austrian Academy of ...

Many gene therapy developers use viral vectors that exhibit specific tissue tropism as delivery vehicles, meaning they preferentially infect certain tissues to deliver the gene therapy cargo ...

Ear tissue punch regeneration has previously been studied in specific strains of Murphy Roths Large mice that have the ability to close 2-mm ear punches with scar-free regeneration.

The regrowth acid The Aldh1a2 gene triggers the production of retinoic acid, a substance derived from vitamin A. Retinoic acid is crucial for cell positioning, growth, and specialization in embryos.

But mapping which microbes participate in gene transfer has been challenging. This new technique gives us a direct way to record this information inside the cells themselves." ...

The Food and Drug Administration’s (FDA) Cellular, Tissue and Gene Therapies Advisory Committee voted 8 to 6 in support of accelerated approval of delandistrogene moxeparvovec (SRP-9001) for the ...

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary ...

New research reveals significant differences in gene expression related to metabolism, inflammation and cardioprotection in the fat tissue of lean and obese mice. These findings could advance the ...