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GPCR Family Receptors (IMAGE)
Key GPCR family receptors that are related to diseases. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or ...
New numbering system standardizes protein domain comparison for better research
Adhesion G protein-coupled receptors (GPCRs) are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for ...
AZoLifeSciences on MSN8d
Scientists Design Ultra-Stable Synthetic Proteins That Could Change Drug Discovery
Innovative designs of GPCRs with enhanced signaling and stability offer new insights for drug discovery and synthetic biology ...
EurekAlert!15d
New numbering system facilitates comparability of protein domains
The GAIN domain plays a central role in the activation of adhesion GPCRs. Until now, research has been limited by the low similarity of the amino acid sequences of different GAIN domains ...
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Programmable G-protein-coupled receptors redefine therapeutic applications.
A recent study published in Nature by a research team from the United States and China introduced a new class of engineered G-protein-coupled receptors (GPCRs) called programmable antigen-gated ...