CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells. Nature Biotechnology , 2020; DOI: 10.1038/s41587-020-0609-x Cite This Page : ...

1 Back to basics (a) The double-helix structure of DNA consists of two linear strands with four bases ­ guanine (G), cytosine (C), adenine (A) and thymine (T). The A bases on one strand pair up with ...

The next step will be testing whether these synthetic bases also work with the main DNA copying enzyme, which would allow them to be used much more widely. After that, ...

Our genomic DNA is comprised of four bases—cytosine (C), thymine (T), guanine (G) and adenosine (A). These bases join together into approximately 3 billion different base pairs, arranged in a ...

For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these ...

However, under certain conditions, a single strand of DNA can fold into a G-quadruplex (G4) structure, which looks like a knot. These knots often form in regions with many guanine (G) bases.

Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A ...

image: Red arrows indicate the nuclear spin axes at the positions of the N3 nitrogen atoms on the guanine (G) bases. Due to the helical structure of DNA, there is an angular deviation in the ...

To date, people have encoded information into DNA the same way nature has, by linking the four nucleotide bases comprising DNA—A, T, C, and G—into a particular genetic sequence.