The enzyme (blue) binds to its substrate (red) to form an enzyme-substrate complex. The enzyme then catalyzes the conversion of the substrate into products (pink), which are released. The enzyme ...

"These findings are in keeping with our 'stalled complex' hypothesis, where it is these enzyme-substrate complexes that trigger neurodegeneration even in the absence of amyloid beta-protein ...

Each enzyme molecule has a special place called the active site where another molecule, called the substrate, fits. The substrate goes through a chemical reaction and changes into a new molecule ...

the enzyme catalase acts on the substrate hydrogen peroxide to make the products water and oxygen. Enzymes can speed up the break down of complex molecules into simpler molecules or the building ...

the enzyme catalase acts on the substrate hydrogen peroxide to make the products water and oxygen. Enzymes can speed up the break down of complex molecules into simpler molecules or the building ...

Glycans can be incredibly complex and branched in structure ... "Most glycosylation enzymes, or glycosyltransferases, do not have an additional lectin, or sugar-recognition domain like GnT ...

With further refinement, the enzyme could be adapted for even more complex reactions, making it a valuable tool in drug development, agricultural chemicals, and materials science. "The ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

Alzheimer's disease is likely caused by stalled protein processing in the brain, according to a new study. The research, published today in eLife, is described by editors as a fundamental study ...