Structural and cellular assays and molecular dynamics simulations reveal the mechanism of action of γ ... and structural modeling to show that the enzyme [MoCu]-CO dehydrogenase interacts with ...

A mechanism that could help scientists harness enzymes for use in drug discovery has been discovered in a research ...

Generations of students have been introduced to this subject with the first and second editions of Enzyme structure and mechanism by Alan Fersht. The detailed introductory descriptions of stopped ...

Instead of the enzyme mechanism described in biochemistry text-books, hen lysozyme hydrolysis was postulated to occur by a ring-opening mechanism based on substrate interactions defined by the active ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

Male ruffs have the ability to eliminate excess sex hormones from their bloodstream. We often associate high testosterone ...

Uncovering similar mechanisms in other organisms could inspire new strategies to target diseases linked to transcription-related genome instability. "We predict that other enzymes likely serve ...

(b. 1964) B.S., 1986, University of Massachusetts, Amherst; Ph.D., 1991, Brown University; National Institutes of Health Postdoctoral Fellow, 1991 – 1994 ...

“It was quite a surprise that this sensor turned out to be an enzyme,” said Chen. “[However], it became very clear after we discovered cGAS [that] it was a very simple and clear mechanism of action.” ...

Redox enzymes are proteins that catalyze oxidation-reduction reactions, which involve the transfer of electrons between ...

Get Instant Summarized Text (Gist) A novel mechanism has been identified that eliminates defective transcriptional elongation enzymes during gene expression. This process involves the ARMC5 ...