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The research team led by Nobel Laureates May-Britt and Edvard Moser at the Norwegian University of Science and Technology (NTNU) is already known for their discovery of the brain’s sense of place. Now ...
According to this model, place cells, along with grid cells found in the entorhinal cortex, act as a scaffold that can be used to anchor memories as a linked series.
A special type of these cells are the so-called grid cells in the entorhinal cortex, a small brain region in the middle temporal lobe. They function like the brain's own GPS, ...
The long-understood model of the studied circuit posits that the hippocampus (HC) receives sensory information about the outside world from entorhinal cortex (EC) surface layers 2 and 3, but sends ...
The entorhinal cortex is critical for communication between the hippocampus, important for memory retrieval and forecasting oneself into the future, and the ventromedial prefrontal cortex, ...
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Scientists have known for a while that Alzheimer’s disease affects some areas of the brain more than others. One key player ...
Brain areas like the entorhinal cortex and hippocampus succumb early to tau tangles, while other areas, like the primary sensory cortices, remain resilient to the disease. In the quest to better ...
It's been recognized for some time that Alzheimer's disease affects brain regions differently and that tau—a protein known to misbehave—plays an important role in the disease. Normally, tau helps ...
Findings suggest that Alzheimer’s risk genes drive tau buildup and spread through both network-based and independent mechanisms.