First, when endothelial cell junctions are disrupted, as they are in some inflammatory conditions 103, leukocytes can easily infiltrate through the exposed subendothelial matrix, ...

In endothelial cells, Bcl-xL up-regulates VEGF-A production, 53 and in platelets, Bcl-xL is a major determinant of the life span. 54 Moreover, platelet-derived epidermal growth factor increases ...

Adherens junctions, the structures that allow cohesion between cells in a tissue, appear to be modulated by endothelial cell-to-cell tugging forces.

Jianmin Yin et al, Oscillatory contractile forces refine endothelial cell-cell interactions for continuous lumen formation ...

(PhysOrg.com) -- University of Pennsylvania bioengineers have demonstrated that the cells that line blood vessels respond to mechanical forces -- the microscopic tugging and pulling on cellular ...

Most leukocytes pass through the endothelial cell junctions, also termed as the paracellular route. In fact, until recently, this was thought to be the only route of endothelial cell migration.

They genetically labeled blood vessel endothelial cell tight junctions with a fluorescent protein to examine if and how tight junctions are involved in autoimmune encephalomyelitis in vivo in ...

Some Aβ can pass through the blood-brain barrier via active transport across endothelial cells (see Deane et al., 2003; Deane et al., 2004). On the other hand, it is still unclear whether Aβ can also ...

The promise of corneal endothelial cell therapy is being able to treat more patients with a less onerous recovery, with better outcomes and perhaps even earlier in their disease.