A syndrome characterized by severe peptic ulcer disease, gastric acid hypersecretion, and non-beta islet cell tumors of the pancreas was first described by Zollinger and Ellison in 1955.

A peptic ulcer is a sore that forms when digestive juices wear away the lining of the digestive system. It may occur in the lining of the stomach or duodenum. A peptic ulcer can affect several ...

Prescription Prilosec is approved by the United States Food and Drug Administration (FDA) to treat GERD, erosive esophagitis, duodenal and gastric ulcers, and conditions such as Zollinger-Ellison ...

Zollinger-Ellison syndrome, multiple endocrine adenomas). In children aged ≥1 year: peptic ulcer disease; GERD with or without esophagitis and ulcerations. In newborns to <1yr: GERD. Duodenal ...

The estimated incidence of ZES in the United States is about 1 case per million individuals per year and about 0.1%-1% among patients with peptic ulcer disease. [6] The mean age at presentation is ...