Spironolactone is a potassium-sparing diuretic. It is a drug most frequently used to lower blood pressure and decrease fluid retention and swelling. It is especially useful in people with liver ...

Elderly. Pregnancy (Cat.C). Nursing mothers. Avoid concomitant potassium-sparing diuretics. Monitor for hyperkalemia with drugs that inhibit the renin-angiotensin-aldosterone sytem (eg ...

A short-acting diuretic such as furosemide produces significant natriuresis during the 6-hour period following drug administration ... to reduced potassium excretion. Potassium-sparing diuretics ...

a potassium-sparing diuretic, improves outcomes in patients with severe heart failure. The drug can sometimes cause life-threatening hyperkalemia, however, when used in combination with ...