Results. Phenolic acids protect against DSS-induced colitis using several different mechanisms. Accordingly, CGA alleviated colitis in a macrophage-dependent manner.

Researchers from Ocean University of China and Qingdao Marine Science and Technology Center published data from a preclinical study that investigated the impact of the quinazolinone derivative MR-2938 ...

DSS-induced UC model mice were created and then randomly assigned to the following groups: control, DSS-treated, 5-amino salicylic acid-treated, BBP low dose, and BBP high dose. Treatment was ...

The macrophage-specific knockout of ECM1 resulted in increased arginase 1 (ARG1) expression and impaired polarization into the M1 macrophage phenotype after lipopolysaccharide (LPS) treatment.

This study presents evidence that dextran sulfate sodium (DSS)-induced colitis exacerbates periodontitis through the activation of the NADPH oxidase 2 (NOX2)/reactive oxygen species (ROS) axis in ...