In the folded fork structure shown in the inset ... other proteins (not shown) are needed for DNA replication. These include a set of initiator proteins to begin each new replication fork at ...

Chromatin structure has a large impact on DNA replication and repair programs. During DNA replication, cells need to disassemble nucleosomes ahead of the replication fork and reassemble them ...

Accurate transmission of the genetic information requires complete duplication of the chromosomal DNA each cell division cycle. However, the idea that replication forks would form at origins of DNA ...

However, the process of DNA replication intrinsically disrupts nucleosomes ahead of the fork raising the question how chromatin structure is maintained across generations. Nucleosomes are re-assembled ...