Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the mechanism by which cells identify and repair a highly toxic form of DNA ...

When environmental stress harms DNA, it can set off a cascade of failures linked to heart conditions, neurodegeneration, and ...

Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the ...

Understanding how DNA damage determines cell fate — DNA repair and cell survival or death — is important for gaining insight into carcinogenesis and in promoting successful cancer therapy.

Abstract Ultraviolet-induced DNA lesions are removed by the nucleotide excision repair (NER) pathway. In global-genome NER (GG-NER), XPC-RAD23B ...

How does a cell know when it’s been damaged? A molecular alarm, set off by mutated RNA and colliding ribosomes, signals ...

The mystery of how cancers build up resistance mechanisms and evade the treatments that should have destroyed them is a ...

DNA damage repaired by antioxidant enzymes Date: June 1, 2023 Source: Center for Genomic Regulation Summary: In crisis, the nucleus calls antioxidant enzymes to the rescue.

New research into mitotic chromosomes has found that they are covered in a liquid-like coating that could allow them to ...

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.