Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published ...

meaning that the ends of each strand are free. In a prokaryotic cell, the DNA forms a circular structure. DNA contains the instructions that are necessary for an organism to grow, develop ...

on one strand and a small pyrimidine base (T or C) on the other chain. The base-pair sequence is usually referred to as the primary structure of DNA. This sequence determines the actual structure ...

A G-quadruplex comprises four guanines from different places along a G-rich strand held together by a special type of hydrogen bonding to form a compact square structure that interrupts the DNA helix.

There is now emerging evidence that this new class of regulators also impinges on the DNA damage response (DDR). Both miRNAs and other small non-coding RNAs (ncRNAs) are induced at DNA breaks and ...

Mitochondrial DNA is compact in structure and typically lacks non-coding regions (introns ... of dsDNA are displaced and separated by a third strand which is base-complementary to one of the ...

DNA achieves this feat of storing, coding and transferring biological information though its unique structure. Check your understanding of this structure and how DNA is replicated with this quiz.

As the two strands of DNA separate, the so-called "coding strand" becomes a template for building a molecule called messenger RNA (mRNA). RNA is similar to DNA, except that it is single-stranded ...

Cells have effective DNA repair mechanisms ... of DNA double-strand breaks causes excessive methylation of NEAT1, which leads to changes in the NEAT1 secondary structure. As a result, highly ...

Newly developed artificial intelligence (AI) programs accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure ... control how the coding DNA is expressed.

The paper describes how alternative structures called flipons set the reading frame to make RNA from DNA. A three-stranded triplex structure creates an open region where DNA is unwrapped.