Early in the history of DNA, thymine replaced uracil, thus solving a short-term problem for storing genetic information — mutation of cytosine to uracil through deamination. Any engineer would ...

Targeted methylation of cytosine residues by S-adenosylmethionine–dependent DNA methyltransferases modulates gene expression in vertebrates. Here we show that cytosine-5-methyltransferases ...

Cytosine (C) modifications such as 5-methylcytosine (mC) and 5-hydroxymethylcytosine (hmC) are important epigenetic markers associated with gene expression and tumorigenesis. However, bisulfite ...

The hydrolytic deamination of cytosine and 5-methylcytosine residues in DNA appears to contribute significantly to the appearance of spontaneous mutations in microorganisms and in human disease. In ...

Cytosine and adenosine base editors (CBEs and ABEs) are integral to molecular breeding, enable precise modification of single-nucleotide polymorphisms (SNPs) in plants, which are crucial for ...

For decades, scientists have known that DNA consists of four basic units -- adenine, guanine, thymine and cytosine. Those four bases have been taught in science textbooks and have formed the basis ...

Cytosine Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).

ISTOCK, BEHOLDINGEYE Base editing is a relatively recent genome-editing technique that swaps one DNA base pair for another, offering researchers the potential to correct harmful, single-nucleotide ...

The fluorescent cytosine, 1,3-diaza-2-oxophenoxazine, can be enzymatically incorporated in high numbers into RNA via end-labeling reactions as well as cell-free transcription.

Guanine (G) is one of the four main nucleobases found in the nucleic acids DNA and RNA, along with along with adenine (A), cytosine (C), and thymine (T). It is a purine base, meaning it has a ...

Thymine is one of the pyrimidine bases found in the nucleic acid of deoxyribonucleic acid (DNA), along with adenine, guanine, and cytosine (A, G, and C, respectively).

DNA and RNA are made up of five organic molecules called nucleobases – adenine, cytosine, guanine, thymine and uracil. That’s the ACGT letter code used to represent DNA, while RNA swaps ...