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Bacterial species study challenges assumption that structural similarity predicts protein behavior
The research compares how two bacterial species—Escherichia coli and Mycobacterium tuberculosis—use a signaling molecule called cyclic AMP (cAMP) to control important cellular functions.
Nature5y
Enhancing cognition through PDE4 regulation
The cyclic nucleotide phosphodiesterase 4 (PDE4) regulates the hydrolysis of the second messenger cyclic AMP. cAMP is a major ... Subsequent structure–activity relationship studies of compounds ...