Findings from a landmark clinical trial in pediatric Crohn's disease show a clear benefit of adding methotrexate to treatment with the tumor necrosis factor inhibitor (TNFi) adalimumab (Humira ...

Crohn's disease can be hard to diagnose because the symptoms may be similar to several other conditions, such as irritable bowel syndrome, and can be missed or look like other conditions on imaging.

The resulting paper, "Early tumour necrosis factor antagonist treatment prevents perianal fistula development in children with Crohn's disease: Post-hoc analysis of the RISK study," appeared in Gut.

In this phase 3b, multicenter, open-label, randomized, controlled trial with blinded assessment of end points, patients with moderate-to-severe Crohn’s disease who had had an inadequate response ...

People with Crohn’s disease often take medicines to help manage their condition and improve their symptoms. Some of these medicines are taken by mouth and stay inside of the digestive tract.

Medically reviewed by Qin Rao, MD Skin tags, medically known as acrochordons, are growths that develop on the skin's surface. Certain health conditions, such as obesity, pregnancy, diabetes, or ...

People with Crohn’s may have lethargy (or fatigue), weakness, swelling, some rectal bleeding, and it can affect the skin, eyes, and other organs of the body. Crohn's can also impact the urinary ...

Crohn’s disease also is a transmural disease, meaning that it can involve the entirety of the bowel wall and that can also lead to complications that we see in Crohn’s disease, ...

The mean age of patients was 42 years, and 58% were men. A majority, 72%, had ulcerative colitis, and 28% had Crohn's disease. Prevalence of Skin Lesions ...