University of Pennsylvania researchers have found a promising new treatment for periodontitis using a component of the immune system called complement, according to a new study in the Journal of ...

Granzyme K activates the entire complement cascade. Nature, 2025; DOI: 10.1038/s41586-025-08713-9 ...

That residual virus could keep the complement system active. Or it’s possible that lingering tissue damage keeps the system engaged. Or maybe it’s something else entirely.

Repeated blood samples turned up important differences in their blood: A group of proteins indicated that a part of the body’s immune system called the complement system remained activated long ...

Now, Wong and team’s study has shown that the complement system may indeed be involved in retinitis pigmentosa but may in fact worsen or curb retinal degeneration, depending on the context.