The occurrence of a chromosomal aberration in a control cell might represent either a spontaneous chromosome aberration or a break related to natural background radiation. A comparison of the 2 ...
In the control patients no single cell contained more than 1 type of chromosomal aberration, nor was more than 1 chromatid exchange or 1 broken chromosome seen per cell. Table 1 Summary of ...
To further complicate matters, the tissues studied by Painter were obtained from a single institutionalized individual who was likely to have had constitutional numerical chromosome aberrations.
Detection rates also depend on the indications for study, with fetal anomalies having the highest rates of chromosome aberrations detected by microarray analysis. Noninvasive prenatal testing has ...
The Cancer Chromosome Aberration Project generates a repository of BAC clones with a resolution of 1–2 megabases. The cytogenetic location of all clones is established by high-resolution ...
Most B chromosomes confer no detectable selective consequences at low numbers, but increased numbers can result in phenotypic aberrations and reduced fertility. To avoid elimination, many B ...
A clonal abnormality is usually defined by the presence of at least two cells with the same aberration (three cells in the case of chromosome loss). Even when the aberration identified is not ...