In eukaryotic cells, the nucleolus is the central site for ribosome biogenesis. It is composed of distinct subcompartments: fibrillar center (FC), dense fibrillar component (DFC), periphery of DFC ...

The nucleolus is where ribosomal RNA (rRNA) is transcribed, processed, and assembled into the building blocks of ribosomes, the molecular machines that make proteins. Researchers discovered that rRNA ...

Focusing on the nucleolus — a droplet-like structure involved in producing the cell’s protein-making machinery — Hnisz and his colleagues showed that immobilizing one of its key scaffolding ...