ABSTRACT Aprotinin is a polypeptide with serine protease inhibitory activity of key enzymes associated with inflammatory, fibrinolytic, and hemostatic pathways. The drug binds directly to the ...

A nonselective extracorporeal blood purifier connected to the cardiopulmonary bypass circuit during nonemergent cardiac surgery may help reduce post-surgical AKI, data show.“There are multiple ...

About The Study: The use of a nonselective extracorporeal blood purification device connected to the cardiopulmonary bypass circuit in a nonemergent population of patients undergoing cardiac ...

Patients were assigned to receive either fresh whole blood that had been collected not more than 48 hours previously (96 patients) or reconstituted blood (104 patients) for bypass-circuit priming.

During open-heart surgery, blood is routed away from the child's heart and lungs through the cardiopulmonary bypass circuit that includes the oxygenation system, creating a bloodless and ...