However, the hetero-pair is the most strongly bound as only this host–guest complex is further stabilized through complementary hydrogen bonding between the nucleotides .

This selective pairing is called ‘complementary base pairing’. A-T pair forms two hydrogen bonds, while C-G pair forms three. The sugar-phosphate chains form the backbone of the ladder-like ...

DNA is comprised of nucleotides, with each nucleotide consisting of a sugar, a phosphate group and a base. Within double stranded DNA (dsDNA), bases from single stranded DNA (ssDNA) will form pairs ...

The unnatural base pair reported now by Hirao and coworkers is formed between the nucleotides, 'Ds' and 'Pa', which are designed to pair not via hydrogen bonds, but rather via hydrophobic packing ().