Dr. Timothy Palzkill, professor of Pharmacology and Chemical Biology and Molecular Virology and Microbiology, and his research team have been studying mechanisms of resistance to the beta-lactam ...

AbbVie has claimed FDA approval for Emblaveo, a new antibiotic product to treat complicated intra-abdominal infections (cIAI) ...

AbbVie has announced that the US Food and Drug Administration (FDA) has approved its Pfizer-partnered Emblaveo ...

The appropriateness of combination therapy for infections caused by gram-negative ... resistant bacteria or fungi. There are no clinical data that suggest that the combination of a β-lactam ...

Infections by multidrug resistant organisms (MDROs) are a global health threat with a worrying increasing trend. In fragile ...

Bacterial cells can also make enzymes that chemically inactivate antibiotics; these include beta-lactamase ... when it comes to antibiotic resistance, gram-negative bacteria have an edge thanks ...

Gram-negative bacteria have three major resistance mechanisms to ... efflux pumps to expel antibiotics and beta-lactamase enzymes to inactivate beta-lactam antibiotics. New antibiotics must ...

Myroides infections are caused by opportunistic bacteria that are primarily found in the environment. These Gram-negative ... exhibited resistance to multiple antibiotics, including beta-lactams ...

Aztreonam–avibactam is a promising treatment for complicated intra-abdominal infections and hospital-acquired or ...

The emergence of resistant to carbapenems Gram-negative bacteria (CR GNB) has severely challenged antimicrobial therapy. Many CR GNB isolates are only susceptible to polymyxins; however ...