This schematic shows the secondary structure of two aptamers ... For example, the FDA-approved aptamer drug Pegaptanib (Macugen) targets vascular endothelial growth factor (VEGF) for the treatment of ...

They found an L-RNA aptamer called L-Apt12-6 that binds specifically to a specific topology of G4 structure: parallel G4. The findings may be beneficial for developing new drugs and treatments for ...

The study was published today in the journal Nature Biotechnology. Once an aptamer binds to its target, its structure alters to release its DNA barcode. For example, the glucose-detecting aptamer ...

TAGCyx can also attach a proprietary ‘mini-hairpin’ structure (patent granted in Japan and pending elsewhere) to the end of the aptamer, in order to improve tolerability to enzymatic ...

York-based biotech firm, the Aptamer Group, has reported “revenue growth, solid cash position and strong technical progress” in its interim results for the six months ending December 31.

By combining the aptamer with a nanoparticle ... Aptamers are DNA or RNA strands that adopt a specific three-dimensional structure, allowing them to bind with high affinity to target molecules.

The structure of the PP7 bacteriophage coat protein ... Berkley to design an aptamer for affinity purification of ribonucleoproteins (Hogg and Collins, 2007). To use the PP7 coat protein as ...