ALK-positive anaplastic large-cell lymphoma (ALCL) represents approximately 3% of non-Hodgkin's lymphomas in adults and 10–30% of paediatric lymphomas. 5 It is a T-cell-derived neoplasm ...

Abstract Purpose To unravel the regulatory network underlying nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) –mediated lymphomagenesis of anaplastic large-cell lymphoma (ALCL) and to discover ...

Anaplastic Large-Cell Lymphoma treatment may involve chemotherapy, targeted therapy, or surgery, depending on the ALK status and type.Early diagnosis and a tailored treatment plan are vital for ...

Anaplastic large-cell lymphoma (ALCL) is a rare type of cancer of white blood cells.

Crizotinib, an inhibitor of the anaplastic lymphoma kinase (ALK) tyrosine kinase, is active in non–small-cell lung cancers that have ALK expression. 1 ALK is fused to several partner genes ...

Rassidakis GZ, Sarris AH, Herling M, Ford RJ, Cabanillas F, McDonnell TJ et al. Differential expression of BCL-2 family proteins in ALK-positive and ALK-negative anaplastic large cell lymphoma of ...

XALKORI is indicated for the treatment of pediatric patients 1 year of age and older and young adults with relapsed or refractory, systemic anaplastic large cell lymphoma (ALCL) that is ALK-positive.

A collaboration between scientists from St. Jude Children's Research Hospital and Dana-Farber Cancer Institute uncovered four proteins that govern the identity of anaplastic large cell lymphoma ...

Large cell lymphoma is a type of non-Hodgkin lymphoma. The most common types of large cell lymphoma are diffuse large B-cell lymphoma (DLBCL) and anaplastic large cell lymphoma (ALCL).

Abstract Purpose To unravel the regulatory network underlying nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) –mediated lymphomagenesis of anaplastic large-cell lymphoma (ALCL) and to discover ...

Anaplastic large cell lymphoma (ALCL) is a rare subtype of non-Hodgkin lymphoma and a form of T-cell lymphoma. Read about symptoms, diagnosis, and treatment.