Actin is a highly abundant protein that ... hence it is difficult to obtain enough filament ends for detailed structure determination. The MPI scientists analyzed not just one, but three distinct ...

The actin filament exists as a structure of the fixed length and bears the muscle contraction and the adjustment on a muscular inside. The circulation and the molecule movements of the polymerization ...

Our skin and mucous membranes are protected by epithelial cells, which form a barrier that defends the body from the outside ...

GAS2 is a cytoskeletal regulator that interacts with both F-actin and microtubules. Here, cryo-EM structures of GAS2 domains ...

A true nucleator must meet several criteria: first, it should accelerate in vitro actin polymerization independently of filament severing ... with an in vivo structure; finally, to understand ...

Actin is a highly abundant protein that ... hence it is difficult to obtain enough filament ends for detailed structure ...

Thin, flexible protein strands called actin filaments act like bones for our cells and are critical for its movement. Supercomputer simulations have helped solve a decades-old mystery of how actin ...

A recently identified bacterial protein structure is contributing to the design of novel anticancer drug delivery systems.

A crystal structure of the F-actin–S1 complex ... followed by binding of ATP to the rearward head to release it from the actin filament. Single-molecule analysis of myosin V (Ref.

Our skin and mucous membranes protect us like vigilant sentinels against the onslaught of harmful pathogens. This extraordinary defense owes its strength to epithelial cells—specialized tissues woven ...

Gamma-actin therefore confers increased rigidity to the apical membrane, forming a network of filaments that is stronger and stiffer than that made up of beta-actin filaments. "This result is ...