"We saw real bundles composed of thousands of fascin molecules and hundreds of actin filaments, and we were able to map their spatial positioning," Gong says. "We saw how the structure of fascin gives ...

The actin filament exists as a structure of the fixed length and bears the muscle contraction and the adjustment on a muscular inside. The circulation and the molecule movements of the polymerization ...

Filopodia help cells move but also aid cancer spread. Scientists have revealed how fascin proteins build these structures, ...

“We saw real bundles composed of thousands of fascin molecules and hundreds of actin filaments, and we were able to map their spatial positioning,” Gong says. “We saw how the structure of ...

Thin, flexible protein strands called actin filaments act like bones for our cells and are critical for its movement. Supercomputer simulations have helped solve a decades-old mystery of how actin ...

Myosin II plays the most important role in cellular force generation. Myosin II molecules self-assemble into filaments with different structures depending on myosin II isoforms and other conditions ...

A crystal structure of the F-actin–S1 complex ... followed by binding of ATP to the rearward head to release it from the actin filament. Single-molecule analysis of myosin V (Ref.

The organization and dynamics of actin filaments must be precisely controlled during these processes, and consequently defects in regulation of the actin cytoskeleton lead to various diseases ...

The mechanism of molecular motors involves a cyclic interaction between the motor domain and the cytoskeletal filament (actin or microtubule). ATP hydrolysis induces conformational changes in the ...