ATP-dependent conformational dynamics in a photoactivated adenylate cyclase revealed by fluorescence spectroscopy and small-angle X-ray scattering Article Open access 02 February 2024 ...

A major user of ATP in many cell types is the actin ... University of Helsinki have now discovered that the abundant and evolutionarily conserved protein,cyclase-associated protein, ...

For example, atrial natriuretic peptide, calcitonin gene–related peptide, and adenosine can activate K ATP channels. 24 Plasma concentrations of these substances are markedly increased in septic ...

The inventors have defined a signal transduction pathway that relates physiological and pharmacological stimuli to ATP release from erythrocytes. This pathway includes the heterotrimeric G proteins Gi ...

The level of remaining ATP is determined using Kinase-Glo® (Promega), a luciferase-based-reagent. Luminescence is inversely proportional to cAMP levels. Thus, as cAMP concentration increases ...

cAMP increasing agents; Forskolin is an inducer that is extensively used in the formation of cAMP. The activation of adenylyl cyclase assists forskolin to increase intracellular cAMP concentrations.

"These findings not only reveal how ATP is loaded to actin in our cells, but also explain why cyclase-associated protein is present in all eukaryotes and is so important for their life," says ...