Cushing's syndrome is a debilitating endocrine disorder which results from hypercortisolemia. While endogenous Cushing's syndrome can be caused by an adrenocorticotrophic hormone (ACTH)-dependent ...

The standard test for differentiating between pituitary and ectopic adrenocorticotropic hormone (ACTH)-dependent Cushing's syndrome is corticotropin-releasing hormone (CRH)-stimulated inferior ...

Endogenous Cushing syndrome is typically due to excess secretion of adrenocorticotropic hormone (ACTH), which drives the adrenal glands to secrete cortisol, most commonly because of a pituitary ...

Stress and some conditions can increase cortisol levels. High cortisol can cause symptoms such as weight gain, acne, and fatigue. Doctors may refer to high cortisol as Cushing syndrome or ...

We often blame stress for everything—from sleepless nights to stubborn weight gain. But did you know your body’s stress hormone, cortisol, could be at the root of more serious health issues ...

Expert Rev Endocrinol Metab. 2013;8(2):183-193. Mitotane reduces cortisol synthesis through the inhibition of 11B-hydroxylase, 18-hydroxylase, 3-α hydroxylase, hydroxysteroid dehydrogenase and ...